結核，超多剤耐性結核 pretomanid
ポリオ(68)
エボラ(80)－コンゴ(民)
● 結核，超多剤耐性結核 pretomanid
PRO/AH/EDR> Tuberculosis, XDR: pretomanid, 6-mo 3-drug oral regimen, FDA approved
Archive Number: 20190816.6626411
情報源 The New York Times 2019年8月14日
南アフリカの患者の臨床治験は，わずか 109人の患者が参加した小規模のものであったが，専門家らはこの結果を groundbreaking と捉えている。The drug regimen は，超多剤耐性結核 extensively drug-resistant tuberculosis に対して 90% の奏効率を示した。14日，食品医薬品局 the Food and Drug Administration (FDA) は，レジメに使用された 3剤 the newest of the 3 drugs を認可した ... the trial では，only 5 pills a day for 6 months を服用するだけで，この錠剤に含まれていたのは，just 3 drugs: pretomanid, bedaquiline and linezolid であった (Someday, the whole regimen might come in just one pill, as HIV drugs do, one expert said.) ... 詳細は原文参照願います。
● 馬インフルエンザ－マリ
PRO/AH/EDR> Equine influenza - Mali: (SG) donkey, morbidity & mortality, lab confirmed
Archive Number: 20190816.6626227
情報源 Horsetalk 2019年8月15日
2019年のこれまでに，西アフリカで 6万頭近いロバが馬インフルエンザ Equine influenza で死亡している
● ポリオ(68)
Poliovirus weekly update as of 14 Aug 2019, World Health Organization
PRO/EDR> Poliomyelitis update (68): global WPV and cVDPV, Benin 1st report
Archive Number: 20190816.6625918
情報源 Global Polio Eradication Initiative / WHO 2019年8月15日
New wild poliovirus cases isolates reported this week:
AFP cases: 5
Environment: 8
Total number of wild poliovirus cases in 2019: 65
Total number of wild poliovirus cases in 2018: 33
New cVDPV isolates reported this week:
AFP cases: 7
Environment: 1
Others: 5
Total number of cVDPV cases (all types) in 2019: 51
Total number of cVDPV cases (all types) in 2018: 104
Headlines
Summary of new viruses this week:
Afghanistan -- 3 wild poliovirus type 1 (WPV1)-positive environmental samples;
パキスタン -- 5 WPV1 cases and 5 WPV1-positive environmental samples;
ナイジェリア -- 2 circulating vaccine-derived poliovirus type 2 (cVDPV2) cases, 1 cVDPV2-positive environmental sample;
コンゴ(民) (DRC) -- 2 cVDPV2 cases;
アンゴラ -- 2 cVDPV2 cases;
ベニン -- 1 cVDPV2 case.
Total global WPV1 cases in 2019: 65
Total global WPV1 cases in 2018: 33
Officially reported cVDPV cases as of 13 Aug 2019:
- アンゴラ: 5 cases in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 21 Jun 2019
- ベニン: 1 case in 2019, onset of paralysis of most recent case: 7 Jul 2019 - Mod.MPP]
- 中央アフリカ共和国: 4 cases in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 23 Jun 2019
- 中国: 1 case in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 25 Apr 2019
- コンゴ(民): 17 cases in 2019 (compared with 11 for the same period in 2018), onset of paralysis of most recent case: 5 Jul 2019
- エチオピア: 1 case in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 20 May 2019
2019
Total global cVDPV cases in 2019: 51
Total global cVDPV cases in 2018: 104
関連項目 Poliomyelitis update (67): Pakistan, Congo DR 20190809.6614717
● エボラ(80)－コンゴ(民)
PRO/AH/EDR> Ebola update (80): Congo DR (NK, IT) cases, summaries, therapeutics, response
Archive Number: 20190816.6624873
[1] Case update
- Tue 13 Aug 2019. WHO dashboard [WHO]
2852 cases
1905 deaths
842 survivors
14 500 case contacts being followed out of 17 000 case contacts
- Fri 16 Aug 2019. South Kivu (Mwenga) ex Beni [The Guardian]
[Also see Washington Post ]
[2] Summary
- Thu 15 Aug 2019. News Scan for 15 Aug 2019 [CIDRAP (Center for Infectious Disease Research and Policy)]
- Wed 14 Aug 2019. News Scan for 14 Aug 2019 [CIDRAP ]
- Tue 13 Aug 2019. Ebola persists in hotspots [CIDRAP ]
- Thu 15 Aug 2019. Update [WHO Disease Outbreak News]→ 厚生労働省検疫所 FORTH
[3] Therapeutics
- Wed 14 Aug 2019. View on treating Ebola [The Guardian]
[4] Response
- Tue 13 Aug 2019. Orphans [UNICEF]
- Wed 14 Aug 2019. Burundi vaccination campaign [WHO Afro]
- Fri 16 Aug 2019. Goma: cross-border meeting [Multisectoral National Committee of the Response to Ebola virus disease, Technical Secretariat]
関連項目 (79): Congo DR (NK, IT) therapeutics, response, research 20190813.6620807
● 原因不明の病気，イチジク－イラク
PRO/PL> Undiagnosed disease, fig - Iraq: (DA)
Archive Number: 20190816.6624679
情報源 Rudaw 2019年8月9日
Akre, Duhok province の当局と農家から，耕作地のほぼ半分が壊滅している原因不明の病気により，2019年のイチジク生産に大きな影響がでると警戒している。
ポリオ(68)
エボラ(80)－コンゴ(民)
● 結核，超多剤耐性結核 pretomanid
PRO/AH/EDR> Tuberculosis, XDR: pretomanid, 6-mo 3-drug oral regimen, FDA approved
Archive Number: 20190816.6626411
情報源 The New York Times 2019年8月14日
南アフリカの患者の臨床治験は，わずか 109人の患者が参加した小規模のものであったが，専門家らはこの結果を groundbreaking と捉えている。The drug regimen は，超多剤耐性結核 extensively drug-resistant tuberculosis に対して 90% の奏効率を示した。14日，食品医薬品局 the Food and Drug Administration (FDA) は，レジメに使用された 3剤 the newest of the 3 drugs を認可した ... the trial では，only 5 pills a day for 6 months を服用するだけで，この錠剤に含まれていたのは，just 3 drugs: pretomanid, bedaquiline and linezolid であった (Someday, the whole regimen might come in just one pill, as HIV drugs do, one expert said.) ... 詳細は原文参照願います。
● 馬インフルエンザ－マリ
PRO/AH/EDR> Equine influenza - Mali: (SG) donkey, morbidity & mortality, lab confirmed
Archive Number: 20190816.6626227
情報源 Horsetalk 2019年8月15日
2019年のこれまでに，西アフリカで 6万頭近いロバが馬インフルエンザ Equine influenza で死亡している
● ポリオ(68)
Poliovirus weekly update as of 14 Aug 2019, World Health Organization
PRO/EDR> Poliomyelitis update (68): global WPV and cVDPV, Benin 1st report
Archive Number: 20190816.6625918
情報源 Global Polio Eradication Initiative / WHO 2019年8月15日
New wild poliovirus cases isolates reported this week:
AFP cases: 5
Environment: 8
Total number of wild poliovirus cases in 2019: 65
Total number of wild poliovirus cases in 2018: 33
New cVDPV isolates reported this week:
AFP cases: 7
Environment: 1
Others: 5
Total number of cVDPV cases (all types) in 2019: 51
Total number of cVDPV cases (all types) in 2018: 104
Headlines
Summary of new viruses this week:
Afghanistan -- 3 wild poliovirus type 1 (WPV1)-positive environmental samples;
パキスタン -- 5 WPV1 cases and 5 WPV1-positive environmental samples;
ナイジェリア -- 2 circulating vaccine-derived poliovirus type 2 (cVDPV2) cases, 1 cVDPV2-positive environmental sample;
コンゴ(民) (DRC) -- 2 cVDPV2 cases;
アンゴラ -- 2 cVDPV2 cases;
ベニン -- 1 cVDPV2 case.
Total global WPV1 cases in 2019: 65
Total global WPV1 cases in 2018: 33
Officially reported cVDPV cases as of 13 Aug 2019:
- アンゴラ: 5 cases in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 21 Jun 2019
- ベニン: 1 case in 2019, onset of paralysis of most recent case: 7 Jul 2019 - Mod.MPP]
- 中央アフリカ共和国: 4 cases in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 23 Jun 2019
- 中国: 1 case in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 25 Apr 2019
- コンゴ(民): 17 cases in 2019 (compared with 11 for the same period in 2018), onset of paralysis of most recent case: 5 Jul 2019
- エチオピア: 1 case in 2019 (compared with 0 for the same period in 2018), onset of paralysis of most recent case: 20 May 2019
2019
Total global cVDPV cases in 2019: 51
Total global cVDPV cases in 2018: 104
関連項目 Poliomyelitis update (67): Pakistan, Congo DR 20190809.6614717
● エボラ(80)－コンゴ(民)
PRO/AH/EDR> Ebola update (80): Congo DR (NK, IT) cases, summaries, therapeutics, response
Archive Number: 20190816.6624873
[1] Case update
- Tue 13 Aug 2019. WHO dashboard [WHO]
2852 cases
1905 deaths
842 survivors
14 500 case contacts being followed out of 17 000 case contacts
- Fri 16 Aug 2019. South Kivu (Mwenga) ex Beni [The Guardian]
[Also see Washington Post ]
[2] Summary
- Thu 15 Aug 2019. News Scan for 15 Aug 2019 [CIDRAP (Center for Infectious Disease Research and Policy)]
- Wed 14 Aug 2019. News Scan for 14 Aug 2019 [CIDRAP ]
- Tue 13 Aug 2019. Ebola persists in hotspots [CIDRAP ]
- Thu 15 Aug 2019. Update [WHO Disease Outbreak News]→ 厚生労働省検疫所 FORTH
[3] Therapeutics
- Wed 14 Aug 2019. View on treating Ebola [The Guardian]
[4] Response
- Tue 13 Aug 2019. Orphans [UNICEF]
- Wed 14 Aug 2019. Burundi vaccination campaign [WHO Afro]
- Fri 16 Aug 2019. Goma: cross-border meeting [Multisectoral National Committee of the Response to Ebola virus disease, Technical Secretariat]
関連項目 (79): Congo DR (NK, IT) therapeutics, response, research 20190813.6620807
● 原因不明の病気，イチジク－イラク
PRO/PL> Undiagnosed disease, fig - Iraq: (DA)
Archive Number: 20190816.6624679
情報源 Rudaw 2019年8月9日
Akre, Duhok province の当局と農家から，耕作地のほぼ半分が壊滅している原因不明の病気により，2019年のイチジク生産に大きな影響がでると警戒している。